Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive devices that deliver a drug in spatial-, temporal- and dosage-controlled fashions have become possible.

Stimuli-sensitive polymersomes have emerged as novel programmable delivery systems in which the release of the encapsulated contents can be readily modulated by the stimulus. The stimuli-responsive release may result in significantly enhanced therapeutic efficacy and minimized possible side effects.

Intrinsic stimuli‐responsive nanocarriers have gained significant interest in the antibacterial research field. In this review, we discuss the potential of these nanocarriers for improved antibacterial drug delivery and highlight further research required to optimize their potential. Stimuli responsive drug delivery systems have emerged as one of the most innovative classes of polymer materials of modern materials science. The polymer architectures exhibiting a large change in their physico chemical behaviors in response to minor signals from the environments have fabricated potentially useful materials for pharmaceutical and biomedical applications. Stimuli-responsive drug delivery systems (DDS) appear as a promising approach to control and target drug delivery. When these DDS are administered, the drug release is activated and then modulated through some action or external input and facilitated by the energy supplied externally.

Carbon-dot-coated novel alginate beads (CA-CD) exhibiting superior stability was successfully used as smart drug delivery vehicle. Garlic Title: Stimuli-Responsive Molecularly Imprinted Polymers for Drug Delivery: A Review VOLUME: 5 ISSUE: 2 Author(s):Francesco Puoci, Francesca Iemma and Nevio Picci Affiliation:Dipartimento di Scienze Farmaceutiche, Universita della Calabria - Edificio Polifunzionale, Arcavacata di Rende (CS) 87036, Italy. Keywords:Molecularly imprinted polymers, stimuli-responsive systems, intelligent drug delivery Traditional drug-delivery systems suffer some drawbacks, especially premature drug release and the lack of diverse stimuli responsiveness. The partnership between suitable solid support-based drug nanocarriers and supramolecular nanovalves led to a variety of gated materials containing supramolecular switches and polymers that are capable of targeted delivery and on-demand release … 2019-07-12 Stimuli-responsive Pd 2 L 4 metallosupramolecular cages: towards targeted cisplatin drug delivery† James E. M. Lewis , a Emma L. Gavey , a Scott A. Cameron a and James D. Crowley * a Among various types of stimuli‐responsive drug delivery systems, reduction‐responsive polymers have attracted great interest. In general, these systems have high stability in systemic circulation, however, they can respond quickly to differences in the concentrations of reducing species in specific physiological sites associated with a pathology. Among them, strategies utilizing stimuli‐responsive delivery systems are highly desirable to regulate glycemia with minimal patient effort and improve the quality of life for diabetic patients.

Adv Drug Deliv Rev. 2013 Nov;65(13-14):1699-715. doi: 10.1016/j.addr.2013.04.011. Epub 2013 Apr 20.

Drug Deliv, 2015; 22(2): 145–155! 2014 Informa Healthcare USA, Inc. DOI: 10.3109/10717544.2014.887157 CRITICAL REVIEW Classification of stimuli–responsive polymers as anticancer drug delivery systems Bita Taghizadeh1, Shahrouz Taranejoo2, Seyed Ali Monemian3, Zoha Salehi Moghaddam4, Karim Daliri5, Hossein Derakhshankhah6, and Zaynab

Reversal of multidrug resistance by stimuli-responsive drug delivery systems for therapy of tumor. 2019-06-14 · This chapter focuses on cyclodextrins and their derivatives as stimuli-responsive polymeric nanocarriers for drug delivery and biomedical applications. The responsive cyclodextrins are able to control drug release in response to either exogenous stimuli such as temperature, light intensity, and magnetic field or endogenous stimuli like pH, enzyme concentration, and oxidation-reduction potential. 2020-10-06 · Multistimuli responsive drug delivery.

The book offers a convincing approach to understanding the basic principles of drug delivery process, their mathematical modeling, different types of drug delivery

Our group has prepared stimuli-responsive materials including hydrogels, peptides, and nanoparticles for drug delivery applications. Intrinsic stimuli‐responsive nanocarriers have gained significant interest in the antibacterial research field. In this review, we discuss the potential of these nanocarriers for improved antibacterial drug delivery and highlight further research required to optimize their potential. Stimuli-responsive drug delivery systems (DDS) appear as a promising approach to control and target drug delivery. When these DDS are administered, the drug release is activated and then modulated through some action or external input and facilitated by the energy supplied externally.

Stimuli-responsive materials, which exhibit changes in one or more properties in response to an external trigger, have gained interest due to their tunability and versatility. Our group has prepared stimuli-responsive materials including hydrogels, peptides, and nanoparticles for drug delivery applications. These materials are responsive to a variety of triggers such as pH, reducing conditions, temperature, glucose, and enzymes that can be tuned based on their chemistry for various The basic mechanisms of stimuli‐responsive drug delivery systems can be described as follows: after injection, the stimuli‐responsive drug delivery system (nanocarriers) accumulates at a tumor site via passive (enhanced permeability and retention effect) or active (receptor–ligand affinity) targeting. Stimuli-responsive particles could find use in numerous applications in the chemical, coatings, cosmetic, detergent and food industries, as well as drug delivery and diagnostics where the stimuli Thermoresponsive and other stimuli-responsive polymers employed in drug delivery systems can be activated via ultrasound stimulation.
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doi: 10.1016/j.addr.2013.04.011. Epub 2013 Apr 20.

2018, Inbunden. Köp boken Stimuli-responsive Drug Delivery Systems hos oss! Stimuli‐responsive nanotherapeutics for precision drug delivery and cancer therapy Yiting Qiao The First Affiliated Hospital; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases; Key Laboratory of Combined Multi‐Organ Transplantation, Ministry of Public Health, School of Medicine, Zhejiang University, Hangzhou, P.R. China Potential stimuli and responses of synthetic stimuli-responsive polymers (adapted from Schmaljohann [6]). Stimuli-responsive polymeric drug delivery is another ﬁeld of controlled drug delivery.
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There are two approaches for designing stimuli-responsive drug-delivery nanoparticles that eciently accumulate at the tumor site, respond to intratumoral or external stimuli, and penetrate tumor cells. One of these approaches involves endogenous stimuli (i.e., enzymes, ions, and redox potential),

Now, scientists Dual stimuli-responsive nanoparticles as novel topical drug delivery systems. Results in Brief.

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Stimuli-sensitive polymersomes have emerged as novel programmable delivery systems in which the release of the encapsulated contents can be readily modulated by the stimulus. The stimuli-responsive release may result in significantly enhanced therapeutic efficacy and minimized possible side effects.

pH-responsive systems take advantage of the significant variations in pH to stimulate localized drug delivery to different regions of the body such as the gastrointestinal tract, tumor microenvironment, or to the endosomal/lysosomal compartments of the cell … 2018-12-01 There are two approaches for designing stimuli-responsive drug-delivery nanoparticles that eciently accumulate at the tumor site, respond to intratumoral or external stimuli, and penetrate tumor cells. One of these approaches involves endogenous stimuli (i.e., enzymes, ions, and redox potential), This review mainly focuses on nanomaterials responsive to the external stimuli used in drug-delivery systems. To overcome the drawbacks of conventional therapeutics to a tumor, the dual- and multi-responsive behaviors of nanoparticles have been harnessed to improve efficiency from a drug delivery … Stimuli-responsive liposomes for drug delivery The ultimate goal of drug delivery is to increase the bioavailability and reduce the toxic side effects of the active pharmaceutical ingredient (API) by releasing them at a specific site of action. 2019-01-01 Stimuli-responsive drug delivery systems (DDS) appear as a promising approach to control and target drug delivery. When these DDS are administered, the drug release is activated and then modulated through some action or external input and facilitated by the energy supplied externally.